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TIAM1 PROTEIN
Descriptors Found:
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DeCS
Descriptor
English
:
T-Lymphoma Invasion and Metastasis-inducing Protein 1
Descriptor
Spanish
:
Proteína 1 de Invasión e Inducción de Metástasis del Linfoma-T
Descriptor
Portuguese
:
Proteína 1 Indutora de Invasão e Metástase de Linfoma de Células T
Synonyms
English
:
TIAM-1 Protein
TIAM1 Protein
T Lymphoma Invasion and Metastasis inducing Protein 1
TIAM 1 Protein
Tree Number:
D12.644.360.325.300.850
D12.776.476.325.300.850
Definition
English
:
A Rho
guanine
nucleotide exchange factor that consists of two
pleckstrin homology domains
flanking central Ras-binding, Dbl-homology (DH) and
PDZ domains
. It stimulates GTP-GDP exchange of rho-like GTPases such as RAC1 PROTEIN; CDC42 PROTEIN; and RHOA PROTEIN, and functions to link extracellular signals to
remodeling
of the
CYTOSKELETON
for
CELL ADHESION
and
CELL MOVEMENT.
See Related
English
:
PDZ Domains
Pleckstrin Homology Domains
History Note
English
:
2018
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
57058
Unique Identifier:
D000075684
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS